Projects

Fundamental Studies of Water Splitting on Model TiO2, RuO2 and Mixed TiO2-RuO2 Catalysts

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Michael Henderson

Project type

Large-Scale EMSL Research

The objective of this project is to provide fundamental insights into the roles of co-catalysts in heterogeneous photocatalytic water splitting over model TiO2 and related semiconducting oxide…

Computational Catalyst Design: Controlling Chemical Transformations to Minimize Environmental Impact

Lead Institution

University of Alabama

Principal Investigator

David Dixon

Project type

Large-Scale EMSL Research

There is a critical need to develop new, renewable sources of energy as well as chemical feedstocks. Biomass is a carbon neutral source of energy and can also address issues related to the…

Interactions between Functionalized Graphene and Electrochemically Active Materials in Advanced Energy Storage System

Lead Institution

University of Arkansas, Fayetteville

Principal Investigator

Jie Xiao

Project type

Large-Scale EMSL Research

The overall goal of this project is to understand the roles of functionalized graphene in energy storage systems spanning from Li-ion, Li-S to Li-air batteries. Specifically, the morphology of…

Towards a complete structure of the intact bacterial cytokinesis machine

Lead Institution

University of Texas Health Science Center at Houston

Principal Investigator

William Margolin

Project type

Large-Scale EMSL Research

All bacteria need to grow and divide in order to proliferate in the environment. This involves duplication of their genetic material, partitioning the copies to daughter cells, and finally…

Electronic and Optical Properties of Doped Complex Oxide Epitaxial Films and Interfaces

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Scott Chambers

Project type

Large-Scale EMSL Research

The effect of A-cation site and anion-site doping, as well as heteroepitaxial interface formation, on the electronic and optical properties of La-based perovskites will be investigated. Specimens…

Experimental Capabilities and Fundamental Science for Geologic Carbon Sequestration: The PNNL In Situ Supercritical Suite (IS3)

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

John Loring

Project type

Large-Scale EMSL Research

This Science Theme proposal requests EMSL access for investigators in the In Situ Supercritical Suite (IS3) component of PNNL's Carbon Sequestration Initiative (CSI). The CSI is a multi-million…

Coupled Surface and Solid-State Charge and Ion Transport Dynamics at Mineral/Water Interfaces: Redox Transformation of the Iron Oxides

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Kevin Rosso

Project type

Large-Scale EMSL Research

This EMSL user proposal requests a continuation of EMSL access for a BES Geosciences supported project led by Dr. Rosso at PNNL. The past three years of research under this BES project we have been…

Determining the Conformational Changes within an Active Enzyme-Substrate System on both Sides of the Reaction.

Lead Institution

University of Colorado at Denver

Principal Investigator

Elan Eisenmesser

Project type

Large-Scale EMSL Research

Our objective is to develop solution-based strategies that directly monitor the physical conformational changes that occur within enzymes, both free and during enzyme catalysis. These strategies are…

Genome-enabled studies of key light-dependent metabolic and regulatory switches governing reductant and carbon partitioning in cyanobacteria

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Alex Beliaev

Project type

Large-Scale EMSL Research

The main goal of this proposal is develop and apply an integrated omics approach for systems-level analysis of photosynthetic metabolism in cyanobacteria that will lead to the identification of key…

Computational Chemical Dynamics of Complex Systems

Lead Institution

University of Minnesota

Principal Investigator

Donald Truhlar

Project type

Large-Scale EMSL Research

The ultimate goal of this project is to develop and apply innovative user-friendly high-performance computing techniques and simulation methods for computational chemical dynamics of complex systems…

Understanding structure-function relationships for developing catalysts for energy storage and production reactions.

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Wendy Shaw

Project type

Large-Scale EMSL Research

The DOE Basic Energy Sciences Energy Frontier Research Center entitled “Center for Molecular Electrocatalysis” (Bullock), the DOE Basic Energy Sciences “Modular Energy-Based Approach to Molecular…

Lipid Activity Probes for the Chemical Proteomic Characterization of Protein Targets

Lead Institution

University of Tennessee

Principal Investigator

Michael Best

Project type

Large-Scale EMSL Research

Lipids including diacyglycerol, phosphatidic acid and the phosphatidylinositol polyphosphates regulate numerous critical biological processes, many of which are aberrant in disease or involved in the…

Interfacial Phenomena in Nanostructured Materials under Irradiation

Lead Institution

University of Tennessee

Principal Investigator

William Weber

Project type

Large-Scale EMSL Research

Nanostructured materials provide the opportunity for tailoring physical, electronic, optical, and biological properties for a variety of technological applications, including novel catalysis, sensors…

Rational Design of Ceramic Interfaces for Environmental Technologies

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Ram Devanathan

Project type

Large-Scale EMSL Research

The aim of this research proposal is to advance the fundamental science needed to safely immobilize nuclear waste in durable ceramic matrices. Crystalline ceramics, including polyphase materials,…

Structural Studies of HIV-1 gp41 MPER and HR-2 Membrane Associated Trimers

Lead Institution

Duke University

Principal Investigator

Leonard Spicer

Project type

Large-Scale EMSL Research

HIV-1 viral-host cell fusion is mediated by the envelope associated gp41 and gp120 protein trimers. The membrane proximal external region (MPER) of gp41 contains the epitopes for the broadly…

Surface/Interface Induced Nucleation and Phase/Structure Evolution and the Correlation to the Performance Boosting/Fading of Advanced Energy Storage Materials

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Xiaolin Li

Project type

Large-Scale EMSL Research

The goal of this proposal is to investigate the surface/interface effect on the synthesis and structure evolution of advanced energy storage materials and the correlation of these changes to the…

Construction of Plug-and-Play Modules Designed using an Integrated Metabolic and Regulatory Model of B. subtilis for Production of High Value Bioproducts Including Isoprene

Lead Institution

Argonne National Laboratory

Principal Investigator

Christopher Henry

Project type

Large-Scale EMSL Research

Rising concerns about fossil fuel shortage and climate change have evoked increasing interest in renewable bioproducts including biofuels. While microbial metabolism can be reengineered for the…

Comparative metaproteomics and metametabolomics of the biomass-degrading microbial community that inhabits the cow rumen

Lead Institution

University of California, Davis

Principal Investigator

Matthias Hess

Project type

Large-Scale EMSL Research

Lignocellulosic plant material is one of the most promising sources of sustainable liquid transportation fuels but the recalcitrant nature of the plant cell wall and the cost of biomass-degrading…

Dynamic Imaging of Structurally Heterogeneous Protein Complexes

Lead Institution

Western University of Health Sciences

Principal Investigator

Thomas Squier

Project type

Large-Scale EMSL Research

Our long-term goal is to identify biological design principles that will enable synthetic biology approaches for bioenergy applications. We hypothesize that the targeted engineering of selected…

Fundamental processes involved in scale up and their role in extracellular electron transfer

Lead Institution

Washington State University

Principal Investigator

Haluk Beyenal

Project type

Large-Scale EMSL Research

Our research group use microbial fuel cells (MFCs) as a tool to study electron transfer processes from biofilms to solid electrodes. Although MFCs have been well studied in the literature,…