Projects

Determination of an unknown protein implicated in radiation resistance in Deinococcus Radiodurans

Lead Institution

Louisiana State University

Principal Investigator

John Battista

Project type

Exploratory Research

Deinococcus radiodurans is one of the most radiation resistant organisms known able to survive after exposure of over 4000 Gy of ionizing radiation. Although it is clear that the DNA is fragmented…

Determination of the proteins induced in mutant forms of Deinococcus radiodurans after exposure to hydrogen peroxide

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Kwong Kwok Wong

Project type

Exploratory Research

The extraordinary repair mechansims of D. radiodurans allow the organism to survive even after exposure to extremely large doses of ionizing radiation. Although it is clear that the DNA is…

Characterization of a putative truncated Calcium-sensing receptor form human ovarian tumors

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Karin Rodland

Project type

Exploratory Research

Rationale: We have determined that the wild-type calcium-sensing receptor [CaR] plays an important role in regulating the proliferative behavior of normal ovarian surface epithelial cells, the cell…

Freeze Drying Synthetic Hematite and Goethite.

Lead Institution

Oak Ridge National Laboratory

Principal Investigator

Eric Pierce

Project type

Exploratory Research

Objective: To obtain Hematite/Goethite powder by freeze drying to remove all water from in contact with the solids. Instrument: Freeze Drying apparatus

Differential Isotopic Esterification for Quantitative Proteome Analysis and de novo Sequenceing

Lead Institution

University of Washington

Principal Investigator

David Goodlett

Project type

Exploratory Research

The proposed method uses differential, isotopic per methyl-esterification of carboxylic acids in peptides as a method for relative quantitation of proteins between solutions of identical proteins…

Multinuclear Transition Metal Complexes for the Activation of Alkanes

Lead Institution

Emory University

Principal Investigator

Keiji Morokuma

Project type

Exploratory Research

(See attached document below)

XPS Studies of Nickel Cobalt Oxide Films

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Charles Windisch

Project type

Exploratory Research

XPS will be used to determine composition of nickel cobalt oxide films fabricated by both solution deposition and sputtering. Information on redox states and stoichiometries, in addition to depth…

Determination of Tungsten Carbide Particle Size and distribution in thermal spray powders and the resultant coatings

Lead Institution

Columbia Basin College

Principal Investigator

David Atteridge

Project type

Exploratory Research

The objective of the this research study is to determine the size and distribution of the Tungsten Carbide particles in both the original powder and in the sprayed coating. The relationship between…

The Interaction of Clays with Iron Metal

Lead Institution

Lewis and Clark College

Principal Investigator

Barbara Balko

Project type

Exploratory Research

The reduction of certain chlorinated organics can be enhanced using clay (smectite) in association with zero-valent iron relative to the reduction with clay or iron alone (Amonette, J.E. Iron Redox…

Use of a Russian Developed Technology (Gubka) for the Treatment of Laboratory & Other DOE Generated Waste.

Lead Institution

Fluor Hanford

Principal Investigator

Larry Burchfield

Project type

Exploratory Research

The purpose of this project is to determine practical parameters for the routine treatment of laboratory and other DOE generated liquid waste. The objectives will be to determine the rates at which…

SEM of aluminum alloy sample

Lead Institution

CANMET-MTL

Principal Investigator

Valery Guertsman

Project type

Exploratory Research

Capture SE images and x-ray maps (Mg, O, Mn)

Microfabrication and CE-MS development

Lead Institution

University of Alabama, Birmingham

Principal Investigator

Sam Wang

Project type

Exploratory Research

A one day visit to the site is requested to learn the current state of the art practiced at the EMSL for capillary electrophoresis combined with mass spectrometry and microfabrication of devices for…

Molecular analysis of cancer by FTICR

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Brian Thrall

Project type

Exploratory Research

Proteomic analysis of wild-type versus cancerous tumor cells.

EPR Spectroscopy of Natural Organic Matter (NOM), Fractions of NOM, and Model Biogeochemical Electron Shuttles

Lead Institution

Oregon Health & Science University

Principal Investigator

Paul Tratnyek

Project type

Exploratory Research

The first study of NOM by electron paramagnetic resonance spectroscopy (EPR), done over 40 years ago, reported that NOM showed paramagnetism. Since 1962, this paramagnetism has been attributed to…

Investigations of Microbial Spore Lysis using Near-IR Laser Irradiation.

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

David Wunschel

Project type

Exploratory Research

The rapid detection of a microorganism in the environment requires the detection of a specific biochemical marker or markers. In characterizing a particular microbial isolate, it is desirable to…

Microelectrode array

Lead Institution

Oregon Health & Science University

Principal Investigator

Jody House

Project type

Exploratory Research

Objective 1: To fabricate an array of electrodes on a Si substrate. The process will require the deposition of oxide/nitride layers and metal deposition, etching, lithography.

X-Ray photoelectron spectroscopic Study of Chemical Bonding and Electronic Structures of the Al2SIO5 Polymorphs

Lead Institution

University of Washington

Principal Investigator

Fumio Ohuchi

Project type

Exploratory Research

Al2SiO5 is crystallized into three distinct polymorphs, named kyanite, andalusite, and sillimanite. Half of the Al-coordinations are 4-fold in sillimanite, 5-fold in andalusite, and 6-fold in…

A comparative Analysis of Two Molecular Surface Generating Techniques

Lead Institution

Eastern Washington University

Principal Investigator

Michael Monek

Project type

Exploratory Research

This project is for partial completion of a Master of Science degree in Mathematics from Eastern Washington University. The objective of the project is to compare Harold E. Trease's Adaptive…

Low angle x-ray characterization of catalyst porosity

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Xiaohong Li

Project type

Exploratory Research

The objective of this research is to improve the scientific and technical understanding of plasma-assisted catalysis (PAC) aftertreatment for heavy-duty diesel engines to meet the proposed EPA…

Low angle x-ray characterization of catalyst porosity

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Xiaohong Li

Project type

Exploratory Research

The objective of this research is to improve the scientific and technical understanding of plasma-assisted catalysis (PAC) aftertreatment for heavy-duty diesel engines to meet the proposed EPA…