Projects

Preparation of Stoichiometric TiO2(110)-(1x1) Surface.

Lead Institution

Fritz-Haber-Institut der Max-Planck-Gesellschaft

Principal Investigator

Alex Bondarchuk

Project type

Exploratory Research

Driving force for investigations of single-crystalline TiO2 surfaces is the wide range of its applications from photocatalysis to degradation of organic pollutants. Rutile TiO2 (110) surface is a…

Developing a systems biology approach for the termite gut microbial isolate Verrucomicrobium sp. strain TAV2.

Lead Institution

University of California, Davis

Principal Investigator

Jorge Rodrigues

Project type

Exploratory Research

Termites are dedicated to transform cellulosic biomass into soluble oligosaccharides, H2, and methane by harboring an entire microbial community. The genome of the Verrucomicrobium sp. TAV2, a member…

Structure and Bonding in Actinide Oxides

Lead Institution

SOLEIL Synchrotron

Principal Investigator

Steven Conradson

Project type

Exploratory Research

We are studying structure and bonding in actinide oxides, which are critical materials in nuclear fuels, actinide corrosion, actinide waste forms and storage, actinide environmental chemistry, and…

Develop fundamental surface science characterization data for use in improving mixed alcohol synthesis catalysts,

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

James White

Project type

Exploratory Research

This project will develop basic information about the surace and bulk nature of various mixed alcohol synthesis catalysts in succsive states, oxide, reduced and used. This information will combine…

Self-assembly and phase transitions in nanofibers and liposomes

Lead Institution

Northwestern University

Principal Investigator

George Schatz

Project type

Exploratory Research

Nanoscale organic and biological materials are of increasing interest for a variety of purposes, from organic electronics to drug delivery, but their structures and self-organization patterns are not…

A Periodic Density Functional Study of VOx Clusters Supported on the Defected Anatase TiO2 (101) Surface

Lead Institution

University of California, Berkeley

Principal Investigator

Alexis Bell

Project type

Exploratory Research

In order to model the chemical reactions catalyzed by supported vanadia, a model needs to be constructed. The defective anatase (101) surface will be modeled by a periodic slab. We have identified at…

Seattle Structural Genomics Center for Infectious Diseases

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Garry Buchko

Project type

Exploratory Research

The Seattle Structural Genomics Center for Infectious Disease (SSGCID) is a consortium of four institutions (Seattle Biomedical Research Institue (SBRI), deCODE biostructures, University of…

Understanding the Structure-Catalytic Function Relationship of Cobalt Based Catalysts for Steam Reforming of Oxygenated Hydrocarbons

Lead Institution

Washington State University

Principal Investigator

Su Ha

Project type

Exploratory Research

The scientific objectives of this application are to fundamentally understand (1) the active sites and (2) how the various support materials and operating conditions influence the activity,…

Determine 3d-structure of chemokine in apo form and in complex with its native receptor by solid state NMR

Lead Institution

Bristol-Myers Squibb

Principal Investigator

Luciano Mueller

Project type

Exploratory Research

Structural biology has significantly accelerated the development of drug leads in protein targets for which 3d structures could be obtained either by XRAY crystallography or by NMR spectroscopy…

Spin valve with perpendicular anisotropy for spin torque experiments

Lead Institution

University of Washington

Principal Investigator

Kannan Krishnan

Project type

Exploratory Research

We propose a research project directed at the study of spin torque effects in multilayer spin valves with perpendicular magnetic anisotropy for magnetic random access memory applications. The spin…

Imaging of a Solid Oxide Fuel Cell Cathode

Lead Institution

Carnegie Mellon University

Principal Investigator

Cristina Amon

Project type

Large-Scale EMSL Research

Microstructure imaging of a solid oxide fuel cell cathode is a necessary component of a computational modeling effort investigating the reactive transport of chromium species in the porous cathode of…

TEM use for analysis of base glasses and doped glasses

Lead Institution

Massachusetts Institute of Technology

Principal Investigator

Lara Rogers

Project type

Exploratory Research

Prepare samples of glass for TEM analysis. Use TEM to look for microdroplet phase separation or micro crystal structure in boro-sodium glass and boro-sodium glass doped with CuO. Take pictures with…

Assessment of TRI Chemical Emisson Factors from Munitions by Real-Time Mass Spectrometric Air Monitoring

Lead Institution

Battelle Columbus

Principal Investigator

Chester Spicer

Project type

Exploratory Research

This will be a component of a larger Battelle project involving application of six different measurement methods to identify and measure emission factors for a large number of Toxic Release Inventory…

Texture, morphology, and stress in PZT thin films

Lead Institution

Washington State University

Principal Investigator

David Bahr

Project type

Exploratory Research

WSU is developing the P3 microengine, a MEMS device that utilizes a composite flexing membrane to generate power by converting mechanical energy to electrical energy. The membrane is made by lead-…

Scanning Mass Spectroscopy of Aerosols

Lead Institution

Monmouth College

Principal Investigator

George Nieman

Project type

Exploratory Research

This project involves attaching a quadrapole mass spectrometer to an existing Enviromental Scanning Electron Microscope. This will allow for the identification of molecular (organic) species attached…

Proteome Analysis of a Breast Carcinoma Cell Line Overexpressing the HER2/neu Oncogene

Lead Institution

University of California, San Francisco

Principal Investigator

Katherine Williams

Project type

Exploratory Research

The application of stable-isotope labeling enables accurate quantitation of relative protein levels. A key aspect of our approach will be the use of isotopically labeled polypeptides, allowing two…

Use of Inductively Coupled Plasma Atomic Emission Spectrometer for Determining Metal Ion Uptake by New Extraction Chromatography or Ion Exchange Resins

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Gregg Lumetta

Project type

Exploratory Research

Extraction chromatography resins have been made for two classes of ligands that have high affinity for actinide ions: bicyclic diamides and Kläui ligands. Batch equilibrium sorption behavior for the…

Protein Signatures of Leukemic Cells

Lead Institution

University of California, San Francisco

Principal Investigator

Katherine Williams

Project type

Exploratory Research

The objective of this project is to determine whether differences in protein expression in acute promyelocytic leukemia with a t(15;17) segregate with treatment outcome. The strategy to identify…

Uranium(VI) sorption onto hematite surfaces

Lead Institution

Forschungszentrum Karlsruhe, Institute for Nuclear Waste Management

Principal Investigator

Dirk Bosbach

Project type

Exploratory Research

Sorption processes on mineral surfaces are relevant for assessing the performance of deep geological nuclear waste deposit sites. Knowledge of basic sorption interactions on a molecular scale is…

Identification and relative expression of membrane proteins in breast cancer cell lines

Lead Institution

University of California, San Francisco

Principal Investigator

Anil Patwardhan

Project type

Exploratory Research

Overview Phase 1: Protein identification in the ?sub-proteome? mixtures from these cell lines will be accomplished using a combination of separation techniques, LC-ESI-MS/MS, and database search and…