Methods for Biological Toxin Identification
EMSL Project ID
49532
Abstract
Biological toxins are of human health and biosecurity concern. Identification of such toxins often relies on enzyme-linked immunosorbent assay (ELISA) methods, but orthogonal approaches are desired. The objective of this project is to develop mass spectrometry-based assays to identify and characterize protein toxins. The potential impact of this investigation is wide-reaching, including application in the public health and security fields. Utilization of EMSL resources, specifically the Q-Exactive HF instrument, will be essential for generation of high quality data for use in downstream applications and to align with end-user instrumentation. Since toxins will either be analyzed in inactive forms or at low levels, no significant toxicity risks are anticipated.
Project Details
Start Date
2016-07-15
End Date
2018-09-30
Status
Closed
Released Data Link
Team
Principal Investigator
Team Members