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Projects

As a scientific user facility, the Environmental Molecular Sciences Laboratory (EMSL) provides expertise, instrumentation, and resources to 250 projects each year. 

EMSL projects displayed on the EMSL web site project page reflect project abstracts and information migrated to this page before April 30, 2024. To review current and past EMSL user projects, visit EMSL Science Central.™ 

 

  • Projects beginning at or after given date.
    Projects ending at or before given date.

Targeted identification of epigenetic determinants of T cell memory

Lead Institution
University of Tennessee
Principal Investigator
Heather Smallwood
Project type
Large-Scale EMSL Research
The ability to recognize previously encountered pathogens and rapidly eliminate them is critical to the immune system, as well as vaccine efficacy. A minute fraction of the millions of T cells…

Rapidly Deployable Sensor Network

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Elizabeth Jurrus
Project type
Exploratory Research
Project Background Emerging networking technology provides unique opportunities for the rapid deployment and operation of clusters of sensor systems. The Rapidly Deployable Sensor Network (RDSN)…

Low Energy Sputtering Experiments using RBS

Lead Institution
NASA Glenn Research Center
Principal Investigator
Michael Nakles
Project type
Exploratory Research
The recent successful demonstration of the NASA Solar electric propulsion Technology Application Readiness (NSTAR) ion thruster on the Deep Space 1 mission has paved the way for future electrostatic…

Proteomics of Morphology Determination in a Fungus

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Linda Lasure
Project type
Exploratory Research
The white rot fungus, Phanerochaete crysosporium, is a saprophytic organism isolated from decaying wood chips. It is one of few organisms that produce ligninase enzymes. These enzymes are required…

NMR/OPTICAL Microscopy Studies of Oral Plaque Ecology

Lead Institution
University of California, Los Angeles
Principal Investigator
Wenyuan Shi
Project type
Large-Scale EMSL Research
Current tooth decay (dental caries) prevention methods include enamel hardening with fluoride and bacterial removal via mechanical and general antimicrobial approaches. These methods are based on the…

Extending Complementary-Metal-Oxide-Semiconductor Technology Into the Future

Lead Institution
Northwestern University
Principal Investigator
David Seidman
Project type
Exploratory Research
With the continuous scaling of microelectronic device dimensions, the variability in MOSFET characteristics, primarily due to the discrete distribution of dopant atoms is a major challenge facing the…

Phenotypic characterization of TCE and PCE degrading Dehalococcoides

Lead Institution
Oregon State University
Principal Investigator
Martin Fisk
Project type
Exploratory Research
We presently have in our laboratory several anaerobic mixed cultures, enriched from contaminated aquifer soils, capable of reductively dechlorinating TCE or PCE fully to ethene in the presence of…

Mass spectrometric analysis of eukaryotic proteosome

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Robert Maxwell
Project type
Exploratory Research
Ubiquitin-dependent proteolysis is catalyzed by the 26S proteasome, a dynamic complex of 32 different proteins whose mode of assembly and mechanism of action is poorly understood. The 26S proteasome…

Degradation of Oxalate Containing Compounds by Soil Microbes

Lead Institution
Oregon State University
Principal Investigator
David Myrold
Project type
Exploratory Research
Ectomycorrihizal mats are macroscopic structures occurring on the forest floor of the HJ Andrews Experimental Forest in the Oregon Cascade Mountains. They can cover up to 25% of the surface area of…

Mass spectrometry analysis of nucleotides/nucleosides

Lead Institution
Washington State University Tri-Cities
Principal Investigator
Kathleen McAteer
Project type
Exploratory Research
We wish to synthesize a number of specifically-labeled DNA oligomers that will be valuable in characterizing the structure and dynamics of damaged DNAs. In order to do this we will isolate 13C and…

Dopamine Replacement Therapy and Parkinson's Disease

Lead Institution
Uppsala University
Principal Investigator
Malin Andersson
Project type
Exploratory Research
Dopamine (DA) replacement therapy with L-3,4-dihydroxyphenylalanine (L-DOPA) is currently the most efficient pharmacotherapy for patients with Parkinson's disease (PD), but with disease…