Projects

As a scientific user facility, the Environmental Molecular Sciences Laboratory (EMSL) provides expertise, instrumentation, and resources to 250 projects each year.

EMSL projects displayed on the EMSL web site project page reflect project abstracts and information migrated to this page before April 30, 2024. To review current and past EMSL user projects, visit EMSL Science Central.™

Biology in Space and Time (BioSaT) Research Campaign

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Scott Baker

Significant research effort is currently aimed at developing cost effective plant biomass deconstruction for biofuel production. Moreover, the recalcitrance of plant cell walls to rapid degradation…

Optimizing Oil Production in Oleaginous Yeast by Cell-Wide Measurements and Genome-Based Models

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Scott Baker

The team at PNNL is using a combination of flow cytometry, microscopy and lipidomics to establish baseline cell biological and metabolite data on lipid production by the W29 strain of Yarrowia…

Enamel biomineralization: A multi-disciplined approach to understand a natural protein-mineral interface. Year 2

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Garry Buchko

The protein amelogenin is the central protein controlling the formation of dental enamel, the hardest tissue in the human body. The protein orchestrates the nucleation, growth, and organization of…

Advancing Materials for Quantum Information Science: CVD Growth and Functionalization of Graphene with Ordered Arrays of Nanodiamonds

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Marvin Warner

Quantum information science is an up and coming area of research aimed to transform computing capabilities in the future. The use of quantum bits, or qubits, in place of traditional bits is predicted…

Development and testing of efficient off-loading strategies for many-body electronic structure methods

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Karol Kowalski

We propose to further modernize the NWChem suite of computational chemistry codes towards effective utilization of the emergent hybrid parallel computer systems based on the Intel Many Integrated…

High Resolution and Mass Accuracy Capability (HRMAC) Development Project

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

David Koppenaal

Access to other FTMS instrumentation is important o successfully and rapidly implement first science applications, to facilitate parallel testing of spectrometer subsystems, and to perform cross…

"HEP Workload Optimization For Parallel Batch Oriented HPC Systems"

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

David Cowley

The High Energy Physics (HEP) computing requirements for current and future experiments require a considerable investment from DOE in hardware infrastructure. The growing costs are driven by the…

Structure and Chemistry at the Buried Solid/Aqueous Solution Interfaces with Advanced Surface Nonlinear Spectroscopy

Lead Institution

Fudan University

Principal Investigator

Hongfei Wang

Solid/aqueous solution interface are ubiquitous and important in energy and environmental research. We propose to investigate benchmark systems in the interface sciences to find novel applications of…

The CCMEE - Culture Collection of Microorganisms from Extreme Environments as a platform for biodiversity research at EMSL

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Sherry Cady

PNNL is home to the CCMEE (Culture Collection of Microorganisms from Extreme Environments), a unique microbial extremophile culture collection. The CCMEE was transferred to EMSL from the University…

Can traces of hydrophobic Euphorbia polymers be found on sand particles from inside the fairy circles of Namibia?

Lead Institution

University of Pretoria

Principal Investigator

Jacobus Meyer

Project type

Limited Scope

There is currently no generally accepted hypothesis on the cause and maintenance of the hundreds of thousands of fairy circles (barren patches) found mainly in the Namibian pro-desert. Several…

Carbon Sequestration Beneath the Active Zone of the Rhizosphere: Insights from Extremophile Ecosystems

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Sherry Cady

To better understand the ultimate fate of carbon sequestered in the subsurface, we are studying carbon sequestration mechanisms in mineralizing extremophile environments. Such ecosystems provide an…

Pan-OMIC characterization of the molecular determinates of uterine receptivity

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Kristin Burnum-Johnson

The overall objective of this research is to identify uterine molecular targets that influence the window of receptivity for embryo implantation. The rational for the proposed research is that a…

OHSU-PNNL NORTHWEST CO-LABORATORY FOR INTEGRATED OMICS

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Karin Rodland

An essential component of the OHSU-PNNL Northwest CoLaboratory for Integrated Omics (CoLab) is the collaborative pursuit of joint research projects that leverage the compelling biomedical model…

EVALUATION OF CEMENT COMPOSITES, ROCKS, AND OTHER MATERIALS CHEMISTRY, PERMEABILITY, AND MORPHOLOGY

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Carlos Fernandez

Through this proposal EMSL will provide experimental resources for enhanced energy production and subsurface science discovery that supports the needs of DOE and the nation. These proposed…

Development of high-throughput metabolomics technologies: Application to studying the flowering time in Arabidopsis thaliana

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

David Hoyt

The future trajectory of metabolomics and its applications largely depends on the analytical capabilities of NMR and MS and their combination. Although the use of both NMR and MS methods is…

Follow-up work on Rhizosphere Underground project (proposal 49147), and work in support of brief one-time exploratory projects within PNNL.

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Alice Dohnalkova

The EMSL Seed LDRD Rhizosphere project has been closed, but I still need to finish some things for 2 publications. I will use the Cryo TEM after hours, or if there is not conflict with the scheduled…

Computational Studies of Complex Matter in the Environment

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Amity Andersen

The goal of this proposal is to develop insight into the complex structure of natural organic matter (NOM) components, including structural changes and dynamics that take place when NOM components…

High-Throughput Multidimensional Bioseparations for Next-Generation Proteomics

Lead Institution

Brigham Young University

Principal Investigator

Ryan Kelly

Mass spectrometry (MS)-based analysis of complex biological samples is essential for biological research including the study of microbiomes. The quality of the analysis is determined not only by the…

Spatially resolving light elements with high resolution chemical analysis for waste forms characterization

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Brian Riley

The primary goal of this user proposal is to gain access to the unique instruments at EMSL that we need to identify and spatially resolve light elements such as Li and B in the presence of other…

Morphology and Protein Profile of Bacterium-Membrane-Formed Nanovesicles

Lead Institution

Washington State University

Principal Investigator

Zhenjia Wang

Project type

Limited Scope

The major goal of this proposal is to access the advanced facility at EMSL to obtain the preliminary data to support our grant application. The structure-activity relationship of nanomaterials…

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