Projects

Structure Determination of Cyclic Siloxane

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

David Nelson

Project type

Exploratory Research

A presumed cyclic siloxane has been observed after the synthesis of specific aromatic co-polymers prepared by hydrosilylation techniques. Some synthetic procedures produce up to 50% of the cyclic…

Molecular Squares

Lead Institution

University of Minnesota

Principal Investigator

Larry Miller

Project type

Exploratory Research

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Metal and Radionuclide Bioremediation by Starvation Promoter-Driven Combinatorial Bacteria

Lead Institution

Stanford University

Principal Investigator

A Matin

Project type

Exploratory Research

We propose to use genetic and protein engineering approaches to construct P. putida strains with superior capacity to remediate chromate and, possibly also radionuclides, at the DOE sites. Such…

Structure-Property Relationships in Thin Film Energy Conversion Materials and Coatings

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Dean Matson

Project type

Large-Scale EMSL Research

We propose to use of EMSL surface analysis, electron microscopy, laser spectroscopy and other analytical capabilities to characterize nanoscale organic and inorganic materials and hybrid thin film…

Nerve Agent Detection Using Enzyme-Coated Nanowires

Lead Institution

Pennsylvania State University

Principal Investigator

Seong Kim

Project type

Large-Scale EMSL Research

We propose a research program to prepare, characterize, and apply enzyme-coated nanowires to the detection of nerve agents. The substrate specificity of enzymatic reactions renders a great potential…

Elemental characterization of ionizer filaments for thermal ionization mass spectrometry (TIMS).

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Mark Engelmann

Project type

Exploratory Research

There has been a great discrepancy in the function of ionizer filaments for use in TIMS in our lab. Seemingly identicle preparation methods continue to give unpredictable results. This proposal…

Soft-Landing of Complex Ions on Surfaces

Lead Institution

Purdue University

Principal Investigator

Robert Cooks

Project type

Large-Scale EMSL Research

Interaction of ions with surfaces is an area of active fundamental research in surface science relevant to a broad range of other scientific disciplines supported by the DOE Office of Science such as…

Molecular-level understanding of transport and optic properties of doped oxide nanoclusters

Lead Institution

University of Idaho

Principal Investigator

You Qiang

Project type

Large-Scale EMSL Research

In this proposal, a research plan to investigate ferromagnetic zinc oxide (ZnO) nanoclusters is outlined. ZnO is a widely studied material due to its wide-band gap energy of 3.3 eV at room…

Molecular Dynamics Study of an Actin Septamer: Testing the Holmes Model and the Hydrophobic Plug Loop Hypothesis

Lead Institution

Northwestern University

Principal Investigator

George Schatz

Project type

Large-Scale EMSL Research

This proposal is in response to the Science Theme Call. We are requesting standard access with non-proprietary status. Actin is a cellular protein which polymerizes into helical filaments. These…

Substrate-specific binding of Staphylococcus adhesins to solid surfaces

Lead Institution

The Ohio State University

Principal Investigator

Steven Lower

Project type

Large-Scale EMSL Research

A nearly universal trait of bacteria is their ability to attach to solid surfaces. Attached cells often form biofilms that are implicated in a significant amount of human infections and have been…

Process images produced by MRM/confocal and CARS/TPC microscopes

Lead Institution

Harvard University

Principal Investigator

Gary Holtom

Project type

Exploratory Research

Access to AFS and SDA is required for substantial bodies of data collected in collaboration with MR Imaging and Cell Biology coworkers. Some custom software (Chris Parkinson) will be used but at the…

Aanalysis of tryptically digested proteins from 2D-PAGE using LC-MS to determine sequence coverage

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Richard Zangar

Project type

Exploratory Research

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Design of micro-cantilever actuators for measuring surface tension of sub microliter volumes applied towards monitoring interfacial processes

Lead Institution

Utah State University

Principal Investigator

David Britt

Project type

Exploratory Research

It is well known that ambient moisture results in a capillary effect between AFM probes and surfaces when scanning in air. This phenomenon has been largely overlooked with respect to cantilever…

Design of micro-cantilever actuators for measuring surface tension of sub microliter volumes applied towards monitoring interfacial processes

Lead Institution

Utah State University

Principal Investigator

David Britt

Project type

Large-Scale EMSL Research

It is well known that ambient moisture results in a capillary effect between AFM probes and surfaces when scanning in air. This phenomenon has been largely overlooked with respect to cantilever…

MICROFABRICATION OF ELECTROSPRAY EMITTER ARRAYS FOR IMPROVED SENSITIVITY IN ELECTROSPRAY IONIZATION-MASS SPECTROMETRY

Lead Institution

Brigham Young University

Principal Investigator

Ryan Kelly

Project type

Exploratory Research

Proposal attached

Microfabrication of Electrospray Emitter Arrays for Improved Sensitivity in Electrospray Ionization-Mass Spectrometry

Lead Institution

Brigham Young University

Principal Investigator

Ryan Kelly

Project type

Large-Scale EMSL Research

Liquid chromatography (LC), combined with mass spectrometry (MS), is an extremely powerful platform for protein analysis, allowing complex mixtures first separated by LC to be further resolved and…

Surface and Interface Studies of Photochemically Initiated Immobilization

Lead Institution

Portland State University

Principal Investigator

Mingdi Yan

Project type

Large-Scale EMSL Research

The ability to precisely control surface and interface properties is of paramount importance in applications ranging from catalysis, adhesion, sensing, to nanoscale devices. Critical to these…

Characterization of mixed monolayers with x-ray photoelectron spectroscopy (XPS)

Lead Institution

Portland State University

Principal Investigator

Li Liu

Project type

Exploratory Research

We are interested in the covalent immobilization of polymer thin films by a photochemically initiated ligation process, with special emphasis on how the surface and interface properties influence the…

The Thickness Measurement of Electrolyte Cast on Mylar Film.

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Sung-tae Hong

Project type

Exploratory Research

The Solid oxide fuel cell (SOFC) is a device converting chemical fuels directly into electrical power. In recent years, considerable advances have been made regarding SOFC technologies. However,…

Column and flow cell experiments to study influence of wetting and mass transfer properties of organic chemical mixtures in vadose zone materials.

Lead Institution

University of Illinois at Urbana-Champaign

Principal Investigator

Albert Valocchi

Project type

Exploratory Research

The project “Influence of wetting and mass transfer properties of organic chemical mixtures in vadose zone materials on groundwater contamination by nonaqeous pahse liquids” has recently been funded…