Projects

Preparing specimens for the scanning electron microscope with Jim Young

Lead Institution

Columbia Basin College

Principal Investigator

Jennifer Von Reis

Project type

Exploratory Research

Thanks to Battelle, Columbia Basin College has a scanning electron microscope (SEM). However, we do not have the equipment to prepare biological specimens. I hope that, working with Jim Young,…

Characterization of the Local Order of Organic Thin Film Material by Combined Atomic Force Microscopy and Optical Microscopy

Lead Institution

Environmental Molecular Sciences Laboratory

Principal Investigator

Dehong Hu

Project type

Large-Scale EMSL Research

This project will develop, demonstrate and publish a new method to study the local order of organic thin film materials. The nanometer scale local order and disorder of organic thin film materials…

Global Proteomic Analysis of Human Ehrlichiosis Agents

Lead Institution

The Ohio State University

Principal Investigator

Yasuko Rikihisa

Project type

Large-Scale EMSL Research

Obligatory intracellular bacteria (belonging to Rickettsia): Ehrlichia chaffeensis and Anaplasma phagocytophilum cause potentially fatal emerging zoonoses: human monocytic ehrlichiosis and human…

Ceria Nanomonitors for Trace Oxygen Monitoring in Portable Energy Systems

Lead Institution

University of Texas at Dallas

Principal Investigator

Shalini Prasad

Project type

Large-Scale EMSL Research

The overarching research objective is development of a portable electrical sensor for rapid detection of trace gases with enhanced sensitivity and specificity. This pilot project seeks to use EMSL…

Understanding field-dependent quadrupolar splitting of 131Xe for applications to surface/material studies

Lead Institution

Colorado State University

Principal Investigator

Thomas Meersmann

Project type

Large-Scale EMSL Research

We propose to study the quadrupolar splitting of 131Xe in the gas phase where a high magnetic field will distort the large electron cloud of 131Xe, thus creating an electric field gradient that will…

Kiln Phosphoric Acid (KPA) Process

Lead Institution

JDC, Inc

Principal Investigator

Joseph Megy

Project type

Large-Scale EMSL Research

JDC, Inc. submitted a successful US Dept. of Agriculture phase I proposal (SBIR-2003-0022) to conduct a basic chemistry and engineering program to forward the KPA process, and carried out the work…

Proteomic Analysis of Differential Growth in Desulfovibrio spp. for a Systems Biology Level Investigation.

Lead Institution

University of Missouri - Columbia

Principal Investigator

Judy Wall

Project type

Large-Scale EMSL Research

Sulfate-reducing bacteria makeup a substantial portion of subsurface microbial communities in general and at DOE contaminated sites in particular. They are capable of reducing, and thus immobilizing,…

Structural analysis of ion-beam-induced amorphous SiC by advanced electron microscopy

Lead Institution

Osaka University

Principal Investigator

Manabu Ishimaru

Project type

Large-Scale EMSL Research

Silicon carbide (SiC) and its composites have been proposed for structural components in future nuclear fusion reactors, because of their high temperature strength, pseudo-ductile fracture behavior,…

An NMR study of the complex formed by viral protein vCCI and human chemokine eotaxin

Lead Institution

University of California, Merced

Principal Investigator

Patricia LiWang

Project type

Large-Scale EMSL Research

Chemokines are essential components of the immune system, causing activation and chemotaxis of leukocytes to sites of infection and inflammation. While the structures of many chemokines are known,…

NON-DESTRUCTIVE EVALUATION OF DAMAGED ANCIENT SCROLLS USING NMR AND PIXE SCANNING TO SEPARATE TEXT FROM THE SCROLL BACKGROUND COMBINED WITH 3D VIRTUAL UNROLLING

Lead Institution

Columbia Basin Imaging

Principal Investigator

Edward Iuliano

Project type

Large-Scale EMSL Research

In 79 A.D. Mt. Vesius in Italy erupted with the resulting pyroclastic flow destroying the nearby cities of Pompeii and Herculaneum. Preserved under 75 feet of ash, a seaside villa owned by Julius…

Development of Single Molecule Force Microscopy Capability to Examine the Moleuclar Mechanism of Lignocellulosic Material Degradation

Lead Institution

The Ohio State University

Principal Investigator

Brian Lower

Project type

Large-Scale EMSL Research

The objective of this proposal is to develop a novel capability based on scanning probe microscopy to examine the enzyme-catalyzed hydrolysis of insoluble lignocellulosic material at the molecular…

Heterogeneous Photochemistry of Organic-Coated Mineral Dust Aerosol

Lead Institution

University of Iowa

Principal Investigator

Vicki Grassian

Project type

Large-Scale EMSL Research

The proposed research will apply state-of-the-art mass spectrometric approaches developed for large complex molecules to interrogate chemical composition of Humic Like Substanses. Specifically, we…

First principles adaptive kinetic Monte Carlo calculations of catalytic reactions at supported nanoparticles

Lead Institution

University of Texas at Austin

Principal Investigator

Graeme Henkelman

Project type

Large-Scale EMSL Research

The goal of this project is to use density functional theory calculations to discover the mechanisms and rates of catalytic reactions on oxide supported metal surfaces and nanoparticles. The focus…

Exploring the mechanisms and kinetics of small peptides towards the search for the global minimum through molecular dynamics simulations

Lead Institution

Technische Universität München

Principal Investigator

Edward Schlag

Project type

Large-Scale EMSL Research

Protein folding is one of the most important and unresolved problems in life science. Given the high complexity of the proteins potential energy surface, it is quite amazing, how nature succeeds to…

Reactivity of primary soil minerals and secondary precipitates beneath leaking Hanford waste tanks

Lead Institution

Pohang University of Science & Technology

Principal Investigator

Wooyong Um

Project type

Exploratory Research

Objectives The primary goals of this project are to (1) quantify reaction kinetics for the dominant mineral dissolution and precipitation reactions that will occur when tank fluids mix with the…

Kinetic Study of Heterogeneous Reaction of Soot with Reactive Oxidants

Lead Institution

Stanford University

Principal Investigator

Hai Wang

Project type

Large-Scale EMSL Research

Heterogeneous reactions occurring between aerosol particles and reactive gaseous species in the atmosphere have significant impacts on atmospheric composition and chemistry, global radiative forcing,…

Surface Selective Studies of Olivine Dissolution by 1H-29Si CP and 25Mg MQMAS NMR

Lead Institution

Pacific Northwest National Laboratory

Principal Investigator

Karl Mueller

Project type

Large-Scale EMSL Research

Mineral trapping is a proposed mechanism for sequestering atmospheric carbon dioxide, allowing permanent confinement of this greenhouse gas. However, the sequestration process requires readily…

Investigation of the metal binding octarepeat region from the human prion using nanoscale computer simulations

Lead Institution

Industrial Summit Technology

Principal Investigator

Eric Yezdimer

Project type

Large-Scale EMSL Research

Several debilitating neurodegenerative diseases, including mad cow and Creutzfeldt-Jakob diseases, are characterized by the production of a misfolded conformation of an endogenous cellular form of…

Ab Initio Studies on Voltage Gating of Ion Channels

Lead Institution

City College of New York

Principal Investigator

Michael Green

Project type

Large-Scale EMSL Research

Abstract: The ab initio and DFT computations proposed here will clarify the mechanism of ion channel voltage gating. Ion channels are proteins in cell membranes that allow passage of K+, Na+, or Ca2+…

Glycolipid Structure, Dynamics and Recognition in a Membrane Environment

Lead Institution

University of Georgia

Principal Investigator

Robert Woods

Project type

Large-Scale EMSL Research

Eukaryotic cells depend on external surface markers, such as glycolipid molecules, to recognize and bind various other molecules as part of normal growth and maturation. As glycolipid molecules are…