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Projects

As a scientific user facility, the Environmental Molecular Sciences Laboratory (EMSL) provides expertise, instrumentation, and resources to 250 projects each year. 

EMSL projects displayed on the EMSL web site project page reflect project abstracts and information migrated to this page before April 30, 2024. To review current and past EMSL user projects, visit EMSL Science Central.™ 

 

  • Projects beginning at or after given date.
    Projects ending at or before given date.

Rhodobacter sphaerodies

Lead Institution
University of Wisconsin, Madison
Principal Investigator
Timothy Donohue
Project type
Exploratory Research
Rhodobacter sphaerodies 2.4.1. is a-3 purple nonsulfur eubacterium with an extensive metabolic repertoire. Under anaerobic conditions, it is able to grow by photosynthesis, respiration and…

The Secretome of Metal-Reducing Shewanella oneidensis

Lead Institution
Georgia Institute of Technology
Principal Investigator
Thomas DiChristina
Project type
Large-Scale EMSL Research
The metabolic reactions catalyzed by metal- and radionuclide-reducing bacteria greatly influence the geochemistry of natural and contaminated environments. One of the more remarkable activities…

NMR Analysis of Bioprocess Samples

Lead Institution
Washington State University Tri-Cities
Principal Investigator
Kathleen McAteer
Project type
Large-Scale EMSL Research
The overall project is directed towards utilization of filamentous fungi for conversion of complex biomass to industrial commodity chemicals biofuels, organic acids or chemical feed-stocks for other…

ETA-Photovoltaics materials Interface optimization

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Timothy Droubay
Project type
Large-Scale EMSL Research
We will provide a fundamental scientific foundation to understand the charge transport in novel oxide-based solar cells, and to tailor the transport by doping and/or interface modification of the…

Electron Transfer Mechanisms in Biofilms

Lead Institution
Washington State University
Principal Investigator
Haluk Beyenal
Project type
Large-Scale EMSL Research
Although interactions of microorganisms with electrodes have been studied in the literature, the mechanisms of electron transfer are still poorly understood. The goal of this proposal is to…

Immunodominance hierarchies in influenza specific CD8+ T cell responses

Lead Institution
University of Tennessee
Principal Investigator
Heather Smallwood
Project type
Large-Scale EMSL Research
The phenomenon of immunodominance has been observed in B cell, CD4+ T cell and CD8+ T cell antigen-specific responses in virtually all types of infection and in tumor immunity model. It is still…

electron induced low-dose hypersensetivity

Lead Institution
Wayne State University
Principal Investigator
Michael Joiner
Project type
Exploratory Research
Following very low acute radiation exposures, an increase in radiosensitivity has been detected at doses below 1 Gy in a number of cell lines in vitro. This phenomenon is termed ?low-dose hyper…

Developing high-performance parallel languages on the SGI Altix

Lead Institution
University of California, Berkeley
Principal Investigator
Dan Bonachea
Project type
Exploratory Research
Our group is working on developing high-performance parallel languages (specifically UPC and Titanium) for modern supercomputers. We'd like to port our implementation of GASNet (a unified, high…

1H AND 13C NMR STUDY OF BRODIFACOUM STEREOCHEMISTRY AND STRUCTURE

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
John Cort
Project type
Exploratory Research
Brodifacoum is a lipid-soluble warfarin derivative that inhibits vitamin K epoxide reductase (VKOR) and exhibits potent anticoagulant activity. Because of its chemical stability and use in numerous…

Solid State NMR Characterization of Hydrogenase

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Exploratory Research
Hydrogenase is a naturally occurring enzyme that efficiently converts H2->2H+ + 2e- and is reversible. Producing synthetic catalysts with these properties is highly desirable, but current analogs…

Isolation of Isotopically-Labeled Nucleic Acids

Lead Institution
Washington State University Tri-Cities
Principal Investigator
Kathleen McAteer
Project type
Exploratory Research
The primary goal of this project is to develop and implement new approaches for using isotopic labels in NMR-based DNA structure determination. 13C and 15N-labeled RNA and DNA will be isolated from…

Metal Ion Binding and Substrate Specificity in Hydroquinone Dioxygenases

Lead Institution
Whitman College
Principal Investigator
Timothy Machonkin
Project type
Exploratory Research
Bacterial pathways for the catabolism of aromatic hydrocarbons are of interest for use in bioremediation of pollutants such as chlorinated arenes. The oxidative ring cleavage step is often the major…

Advanced IMPROVE Studies

Lead Institution
Desert Research Institute
Principal Investigator
Douglas Lowenthal
Project type
Exploratory Research
The proposed collaboration with Dr. Lizabeth Alexander of PNNL will enable continuous measurement of size-resolved aerosol chemical composition using the EMSL high resolution time-of-flight Aerosol…

Fluorescence Microscopy of Cells and Particles.

Lead Institution
Harvard University
Principal Investigator
Gary Holtom
Project type
Exploratory Research
Response of live cells to particles will be studied by analyzing images taken with the fluorescence microscope.

Gold - Acounting and Allocation Management

Lead Institution
Cluster Resources, Inc.
Principal Investigator
Scott Jackson
Project type
Exploratory Research
Gold is an accounting and allocation manager being developed as part of the Scalable Systems Software SciDAC project. Gold is a next generation application which is slated as a replacement to the…