Nanospray Desorption Electrospray Ionization Mass Spectrometry
The Nanospray Desorption Electrospray Ionization Mass Spectrometer (nanoDESI) is used for a variety of environmental research projects that are relevant to atmospheric aerosol chemistry, aquatic and soil chemistry, and mass spectrometry imaging of biological samples. This resource is available to researchers worldwide through the EMSL User Program.
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Atom Probe Tomography
Atom proble tomography is a material analysis technique available at the Environmental Molecular Sciences Laboratory (EMSL) through the EMSL User Program.
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Mass Spectrometry Imaging
The Environmental Molecular Sciences Laboratory's mass spectrometry capabilities allow researchers to investigate the spatial distribution of molecules within biological samples. Mass spectrometry imaging resources are available to researchers who submit proposals and are awarded funding through the EMSL User Program.
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Environmental Scanning Electron Microscopy for Atmospheric Research
The Environmental Molecular Sciences Laboratory's scanning electron microscope offers a variety of detectors and an integrated custom-built platform for atmospheric research. These resources are available to the research community through open calls for proposals.
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Ice Nucleation Chamber
The Environmental Molecular Sciences Laboratory (EMSL) has a custom-built ice nucleation chamber that researchers can use to study properties of atmospheric particles or aerosols in situ, under user-defined conditions. The chamber can be accessed through the EMSL User Program's open calls for proposals.
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Single Particle Mass Spectrometry
The Environmental Molecular Sciences Laboratory's single particle mass spectrometer, miniSPLAT, is used to characterize in situ and real-time physicochemical properties of individual particles, with unparalleled sensitivity, sizing precision, mass-spectral quality, and temporal resolution.
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Photoacoustic Spectrometer
The Environmental Molecular Sciences Laboratory's Photoacoustic Extinctiometer (PAX) measures optical properties of aerosols in real-time. PAX is available to researchers through the EMSL User Program.
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Fourier Transform Infrared Spectroscopy and Microscopy
The Environmental Molecular Sciences Laboratory offers Fourier Transform Infrared (FTIR) spectrometry instrumentation for studying atmospheric chemistry, biological processes, and bioenergy production. This resource is available through the EMSL User Program.
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Cell-Free Expression Pipeline
The Environmental Molecular Sciences Laboratory's cell-free expression pipeline provides fast access to proteins or heteromeric complexes of interest.
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Coherent Anti-Stokes Raman Scattering and Stimulated Raman
Inverted scanning confocal microscope equipped for chemical and biological imaging. Label-based, label-free, and time-resolved imaging of cellular and subcellular dynamics possible in biosystems…
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Cryogenic Focused Ion Beam-Scanning Electron Microscopy
The cryogenic focused ion beam-scanning electron microscope (cryo-FIB-SEM) is a semi-automated instrument that provides pseudo-three-dimensional imaging of thick samples with ~10-nm resolution or…
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Fluorescence-Activated Cell Sorting
The Environmental Molecular Sciences Laboratory (EMSL)'s Fluorescence-Activated Cell Sorter (FACS) allows collection and enrichment of unique populations of cells, or single cells, from a heterogenous culture.
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Laser Capture Dissection Microscope
The Environmental Molecular Sciences Laboratory's laser capture dissection microscope is available to the scientific community through open calls for proposals. The microscope allows researcher to collect samples of unique populations of cells based on specific morphology or fluorescent labeling.
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Nanodroplet Processing in One Pot for Trace Samples (NanoPOTS)
The Environmental Molecular Sciences Laboratory offers a microfluidic sample preparation platform called Nanodroplet Processing in One Pot for Trace Samples, or nanoPOTS, for proteomics profiling of biological samples.
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Nanoscale Fourier Transform Infrared Spectroscopy
Nanoscale Fourier transform infrared spectroscopy (nano-FTIR) is a high-resolution chemical imaging system, which combines the nanoscale spatial resolution of atomic force microscopy with the…
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Nanoscale Secondary Ion Mass Spectrometry
The Environmental Molecular Sciences Laboratory (EMSL) offers the nanoscale secondary ion mass spectrometry (NanoSIMS) capability through the EMSL User Program's open calls for proposals.
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Super Resolution Fluorescence Microscope
The Environmental Molecular Sciences Laboratory offers super resolution fluorescence microscopy instrumentation for analyzing cell-cell and cell-environment interactions and in-situ cellular processes.
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Raman Atomic Force Microscopy
The Environmental Molecular Sciences Laboratory's Raman atomic force microscopy resources are available to the scientific community through open calls for proposals.
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Time-of-Flight Secondary Ion Mass Spectrometry
Time-of-flight (ToF) secondary ion mass spectrometry (SIMS) is available at the Environmental Molecular Sciences Laboratory through open calls for proposals.
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Transmission Electron Microscopy-Energy Dispersed X-ray and Electron Energy-Loss Spectroscopy
The Environmental Molecular Sciences Laboratory (EMSL) develops and deploys advanced scanning transmission electron microscopy and associated spectroscopy capabilities, in particular under in-situ imaging condition, for the EMSL User Program.
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