Atom Probe Tomography
Atom proble tomography is a material analysis technique available at the Environmental Molecular Sciences Laboratory (EMSL) through the EMSL User Program.
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Mass Spectrometry Imaging
The Environmental Molecular Sciences Laboratory's mass spectrometry capabilities allow researchers to investigate the spatial distribution of molecules within biological samples. Mass spectrometry imaging resources are available to researchers who submit proposals and are awarded funding through the EMSL User Program.
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Cell-Free Expression Pipeline
The Environmental Molecular Sciences Laboratory's cell-free expression pipeline provides fast access to proteins or heteromeric complexes of interest.
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Coherent Anti-Stokes Raman Scattering and Stimulated Raman
Inverted scanning confocal microscope equipped for chemical and biological imaging. Label-based, label-free, and time-resolved imaging of cellular and subcellular dynamics possible in biosystems…
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Cryogenic Focused Ion Beam-Scanning Electron Microscopy
The cryogenic focused ion beam-scanning electron microscope (cryo-FIB-SEM) is a semi-automated instrument that provides pseudo-three-dimensional imaging of thick samples with ~10-nm resolution or…
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Fluorescence-Activated Cell Sorting
The Environmental Molecular Sciences Laboratory (EMSL)'s Fluorescence-Activated Cell Sorter (FACS) allows collection and enrichment of unique populations of cells, or single cells, from a heterogenous culture.
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Laser Capture Dissection Microscope
The Environmental Molecular Sciences Laboratory's laser capture dissection microscope is available to the scientific community through open calls for proposals. The microscope allows researcher to collect samples of unique populations of cells based on specific morphology or fluorescent labeling.
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Nanodroplet Processing in One Pot for Trace Samples (NanoPOTS)
The Environmental Molecular Sciences Laboratory offers a microfluidic sample preparation platform called Nanodroplet Processing in One Pot for Trace Samples, or nanoPOTS, for proteomics profiling of biological samples.
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Nanoscale Fourier Transform Infrared Spectroscopy
Nanoscale Fourier transform infrared spectroscopy (nano-FTIR) is a high-resolution chemical imaging system, which combines the nanoscale spatial resolution of atomic force microscopy with the…
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Nanoscale Secondary Ion Mass Spectrometry
The Environmental Molecular Sciences Laboratory (EMSL) offers the nanoscale secondary ion mass spectrometry (NanoSIMS) capability through the EMSL User Program's open calls for proposals.
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Super Resolution Fluorescence Microscope
The Environmental Molecular Sciences Laboratory offers super resolution fluorescence microscopy instrumentation for analyzing cell-cell and cell-environment interactions and in-situ cellular processes.
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Raman Atomic Force Microscopy
The Environmental Molecular Sciences Laboratory's Raman atomic force microscopy resources are available to the scientific community through open calls for proposals.
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Time-of-Flight Secondary Ion Mass Spectrometry
Time-of-flight (ToF) secondary ion mass spectrometry (SIMS) is available at the Environmental Molecular Sciences Laboratory through open calls for proposals.
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Transmission Electron Microscopy-Energy Dispersed X-ray and Electron Energy-Loss Spectroscopy
The Environmental Molecular Sciences Laboratory (EMSL) develops and deploys advanced scanning transmission electron microscopy and associated spectroscopy capabilities, in particular under in-situ imaging condition, for the EMSL User Program.
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Soil Incubation
The Soil Incubation Laboratory at the Environmental Molecular Sciences Laboratory offers environmental chambers and incubators for conducting controlled lab studies on soils, sediment, and other environmental samples.
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X-ray Photoelectron Spectroscopy
Researchers can access X-ray photoelectron spectroscopy at the Environmental Molecular Sciences Laboratory (EMSL) to provide information on the chemical nature and state of detected elements. This resource is available through the EMSL User Program.
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cellenONE
cellenONE is a single-cell isolation and dispensing platform that is used for transcriptomics and proteomics research. Scientists can access and apply cellenONE to their research by submitting a proposal to an open call at the Environmental Molecular Sciences Laboratory (EMSL).
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Controlled Combustion System
The Environmental Molecular Sciences Laboratory's controlled combustion system mimics real-life combustion conditions around aerosols produced and improves understanding of aerosol formation, properties, and the effects on ecosystem.
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Size and Time-Resolved Aerosol Collector
The Environmental Molecular Sciences Laboratory’s multifunctional size and time-resolved aerosol collector (STAC) is used to investigate how aerosol physicochemical properties evolve.
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Activity-Based Probes
Activity-based probes are available to researchers through the Environmental Molecular Sciences Laboratory (EMSL) User Program to help gain spatio-temporal understanding of functional proteins in biochemical processes.
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