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Wendy Shaw

Institution
Pacific Northwest National Laboratory
ORCID
ORCID logo 0000-0002-4696-7415

Projects

Biomineralization peptides structure and function

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Exploratory Research
My work includes looking at biomineralization peptides on inorganic surfaces to determine their structure and relate that to function. In order to do this, I must confirm that I have a pure peptide…

Protein Structure and Surface Interactions of an Enamel Protein

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Capability Research
The structure and protein-surface interaction of an enamel protein, amelogenin, will be investigated both on and off of hydroxyapatite using solid state NMR. The formation of nanospheres (protein…

Solid State NMR Characterization of Hydrogenase

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Exploratory Research
Hydrogenase is a naturally occurring enzyme that efficiently converts H2->2H+ + 2e- and is reversible. Producing synthetic catalysts with these properties is highly desirable, but current analogs…

Bio-Inspired Homogeneous Catalysts for Energy Storage and Production

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Molly O'Hagan
Project type
Large-Scale EMSL Research
This proposal is in response to the Energy Materials and Processes Science Theme proposal call requesting resources to support three research programs at PNNL: the DOE Basic Energy Sciences &quot…

EPR characterization of hydrogenase

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Limited Scope
Hydrogenase is a naturally occurring enzyme that efficiently converts H2 ->2H+ + 2e- and is reversible. Producing synthetic catalysts with these properties is highly desirable, but current…

Hydrogen Storage Materials

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Capability Research
The increasing demands for clean energy sources that do not add more carbon dioxide and other pollutants to the environment have resulted in increased attention worldwide to the possibilities of a …

Hydrogen Storage Materials

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Capability Research
The increasing demands for clean energy sources that do not add more carbon dioxide and other pollutants to the environment have resulted in increased attention worldwide to the possibilities of a …

Bioinspired electrocatalysts for small molecule activation.

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Exploratory Research
The proposed EMSL research is in support of three DOE Basic Energy Sciences research programs that focus on the development of new classes of electrocatalysts for important energy storage and energy…

Hydrogen Storage Materials

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Capability Research
The increasing demands for clean energy sources that do not add more carbon dioxide and other pollutants to the environment have resulted in increased attention worldwide to the possibilities of a …

Draws Implementation

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Capability Research
Naturally occurring biominerals possess an impressive array of strength, order and nanostructure. These properties are the direct result of protein controlled nucleation and templated mineral growth…

Enamel biomineralization: Solution- and solid-state NMR

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Garry Buchko
Project type
Exploratory Research
Dental enamel, the layer of elongated carbonated hydroxyapatite on the outer layer of the tooth, is the hardest tissue in the human body. It needs to be strong because it cannot repair itself nor can…

Nanocrystalline MoS2 catalysts

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Exploratory Research
Characterization by SEM of nanocrystalline MoS2 solids. We have 4 samples that we would like to analyze by SEM for nanostructure.

Computer-aided Design of a Catalytic Proton Channel

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Exploratory Research
The objective of the proposed research is to incorporate a rationally designed proton channel into homogeneous catalysts using advanced enzyme design methodology combined with superior molecular…

Understanding proton movement in [FeFe]-hydrogenase

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Joseph Laureanti
This proposed work ultimately aims to understand enzymatic design principles using a highly studied and well-known system by creating a series of mutant metalloenzymes to probe the validity and…

Bioinspired Electrocatalysts for Energy Storage and Production Reactions.

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Exploratory Research
Electrocatalysts can convert electrical energy into chemical bonds in fuels, such as H2. In the reverse reaction, electrocatalysts can use the fuel to generate electrical energy on demand. This…

Understanding proton movement in [FeFe]-hydrogenase

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Joseph Laureanti
This proposed work ultimately aims to elucidate enzymatic design principles for proton transfer. We will employ the smallest and most NMR “friendly” version of this highly studied and well-known…

T1 and T1ro Measurements of Carbons

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Capability Research
The experiments I am proposing to do are T1 and T1ro measurements of carbons, thus I will need a 13C, 1H probe. I would like to use the 500 narrow bore to do these experiments.

Solid State NMR to investigate protein interactions at interfaces

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Capability Research
Naturally occurring biominerals possess an impressive array of strength, order and nanostructure. These properties are the direct result of protein controlled nucleation and templated mineral growth…

Surface area measurements

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Exploratory Research
We need access to the BET to determine the surface area of synthesized hydroxyapatite. The hydroxyapatite will be used to bind peptides and proteins relevant to biomineralization. Functional and…

Surface Characterization of Calcium Phosphates

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Large-Scale EMSL Research
Heterogeneous nucleation is important in the development of biominerals such as bone, teeth and mollusk shells, but often, initial nucleation events are not understood at a mechanistic level(1). It…

Surface Characterization of Calcium Phosphates

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Exploratory Research
Determination of calcium phosphate phases are important in many biomineralization processes from nucleation to growth to inhibition. The factors controlling phase in materials development are…

Structure-function correlations of proteins in enamel formation

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Large-Scale EMSL Research
Heterogeneous nucleation is important in the development of biominerals such as bone, teeth and mollusk shells, but often, initial nucleation events are not understood at a mechanistic level. It is…

SEM of protein assisted calcium phosphate nucleation

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Wendy Shaw
Project type
Exploratory Research
Proteins are often thought to aid in biomineralization and nucleation of the mineral is one process that some proteins have been seen to contribute to. To date, amelogenin, a key component in enamel…