Nanospray Desorption Electrospray Ionization Mass Spectrometry
The Nanospray Desorption Electrospray Ionization Mass Spectrometer (nanoDESI) is used for a variety of environmental research projects that are relevant to atmospheric aerosol chemistry, aquatic and soil chemistry, and mass spectrometry imaging of biological samples. This resource is available to researchers worldwide through the EMSL User Program.
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Lipidomics
The Environmental Molecular Sciences Laboratory (EMSL) offers liquid chromatography tandem mass spectrometry (LC-MS) for lipidomics research, which is available through the EMSL User Program.
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Mass Spectrometry Imaging
The Environmental Molecular Sciences Laboratory's mass spectrometry capabilities allow researchers to investigate the spatial distribution of molecules within biological samples. Mass spectrometry imaging resources are available to researchers who submit proposals and are awarded funding through the EMSL User Program.
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Pyrolysis Gas Chromatography-Mass Spectrometry
The Environmental Molecular Sciences Laboratory offers pyrolysis–gas chromatography–mass spectrometry for method of chemical analysis of environmental applications, including the identification and characterization of micro- and nano-plastic contamination.
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Real Time Mass Spectrometry
The Environmental Molecular Sciences Laboratory (EMSL)'s real time mass spectrometry resources are available to researchers around the world through the EMSL User Program for understanding gas exchanges in diverse biological and environmental systems
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Super resolution structured illumination and Airyscan fluorescence microscope
The Airyscan module, mounted on the confocal fluorescence microscope, provides 3D imaging with a superior detection sensitivity and speed compared when compared to the standalone structured illumination microscopy system or classic confocal microscope. This capability is available at the Environmental Molecule Sciences Laboratory (EMSL) through the EMSL User Program.
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Confocal, Fluorescence Lifetime Imaging, and Multi-Photon Fluorescence Microscope
The Environmental Molecular Sciences Laboratory (EMSL) offers confocal, fluorescence imaging, and multi-photo fluorescence microscope system for environmental and biological research. These resources are available through EMSL's open calls for proposals.
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Lattice Light Sheet
The Lattice Light Sheet microscope is a tool for imaging living organisms or cells with up to single molecule resolution. This resource is available at the Environmental Molecular Sciences Laboratory (EMSL), a Department of Energy user facility.
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Liquid State NMR for Metabolomics
The Environmental Molecular Sciences Laboratory (EMSL) offers liquid state nuclear magnetic resonance capabilities for metabolomics research through the EMSL User Program.
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Liquid State NMR for Organic Matter/Complex Mixtures
The Environmental Molecular Sciences Laboratory's liquid state nuclear magnetic resonance capabilities for studying mixtures or pure compounds.
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Nanodroplet Processing in One Pot for Trace Samples (NanoPOTS)
The Environmental Molecular Sciences Laboratory offers a microfluidic sample preparation platform called Nanodroplet Processing in One Pot for Trace Samples, or nanoPOTS, for proteomics profiling of biological samples.
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Bottom-Up (Fragmented) Proteomics
The Environmental Molecular Sciences Laboratory has a variety of proteomics resources available to the scientific community through open calls for proposals.
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Top-down (Intact) Proteomics
The Environmental Molecular Sciences Laboratory's top-down proteomics resources enable researchers to measure stoichiometry of protein-protein, protein-nucleic acid, protein-ligand, and protein-metal complexes. Resources are also available for precisely defining “proteoforms” at the intact protein level. These capabilities are accessible through open calls for proposals.
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Mass Spectrometry for Organic Matter Analysis
The Environmental Molecular Sciences Laboratory offers Fourier transform ion cyclotron resonance (FTICR) mass spectrometry resources for analyzing organic matter. This instrumentation is available to researchers through open calls for proposals.
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Mass Spectrometry for Metabolomics
The Environmental Molecular Sciences Laboratory has state-of-the-art and advanced mass spectrometry platforms to perform a full range of metabolomics studies. These resources are available for use at no cost to researchers around the world through EMSL's open calls for proposals.
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Controlled Combustion System
The Environmental Molecular Sciences Laboratory's controlled combustion system mimics real-life combustion conditions around aerosols produced and improves understanding of aerosol formation, properties, and the effects on ecosystem.
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Size and Time-Resolved Aerosol Collector
The Environmental Molecular Sciences Laboratory’s multifunctional size and time-resolved aerosol collector (STAC) is used to investigate how aerosol physicochemical properties evolve.
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NanoLive
The NanoLive 3D Cell Explorer CX-A is a microscopy platform available through the EMSL User Program. This platform is designed for repeat observations over time on bacterial and eukaryotic cells.
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Graph Identification of Proteins in Tomograms (GRIP-Tomo)
The Environmental Molecular Sciences Laboratory (EMSL) is developing a capability that will allow scientists to mine data for patterns using the algorithm of graph identification of proteins in tomograms (GRIP-Tomo), which will improve protein identification and faster structure determination.
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TerraForms
TerraForms is a group of platforms of custom-designed synthetic environments, microfluidics technologies, and in-house instrumentation to simulate soil properties and visualize soil microbial and plant community dynamics.
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