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Scott Baker

Institution
Environmental Molecular Sciences Laboratory

Projects

Organelles promoting high level terpenoid biosynthesis in filamentous fungi.

Lead Institution
United States Department of Agriculture - Agricultural Research Service Cereal Disease Laboratory
Principal Investigator
Harold Kistler
Project type
FICUS Research
Terpenoid compounds are a promising source of renewable biofuels that have many favorable characteristics such as high energy content and compatibility with existing energy-use technologies. While…

Yarrowia lipolytica for biotechnology and synthetic biology

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Scott Baker
The team at PNNL is using a combination of flow cytometry, microscopy and lipidomics to establish baseline cell biological and metabolite data on lipid production by the W29 strain of Yarrowia…

Agile BioFoundry

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Scott Baker
This proposed EMSL Resource Owner project, is a sub-project supporting two DOE-EERE-BETO supported PNNL projects: FY16-17 four-national laboratory “Agile BioFoundry” (ABF) seed project and a larger…

Yarrowia lipolytica for biotechnology and synthetic biology

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Erin Bredeweg
The team at PNNL is using a combination of flow cytometry, microscopy and lipidomics/metabolomics to establish baseline cell biological and metabolite data on DNA agility in eukaryotic organisms, and…

Agile BioFoundry

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Jon Magnuson
This proposed EMSL Resource Owner project, is a sub-project supporting DOE-EERE-BETO supported PNNL-national laboratory Agile BioFoundry (ABF) project. PNNL’s effort for this project, which includes…

A proteomic approach to the study of Neurospora crassa ribosomal dynamics

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Scott Baker
Project type
Exploratory Research
We propose to apply the LC/MS/MS global proteomics approach to study eukaryotic ribosome dynamics using the model filamentous fungal organism, Neurospora crassa. The experimental tractability and…

Proteomic analysis of Fusarium graminearum sexual development

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Scott Baker
Project type
Exploratory Research
Fusarium graminearum is a major pathogen and the cause of mycotoxin contamination of cereal crops including corn, wheat and barley. The economic impact of F. graminearum infection of these crops is…

NWBio

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Scott Baker
The goal of "NWBio" project is to leverage computational chemistry and physics methods to develop a new generation of predictive modeling and simulation tools for biology. This project…

Enabling Agile Biomanufacturing with Leading Edge Analytical Biology

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Mark Butcher
This proposed EMSL User project supports a larger multi-lab "Agile Biomanufacturing" project (LBNL, PNNL, SNL). Through the EMSL’s leading edge analytical biology, GC and LC mass…

Proteomics of Filamentous Fungi

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Ellen Panisko
Project type
Exploratory Research
As part of the PNNL Biobased Products Initiative, an LDRD proposal entitled “Proteomics of Filamentous Fungi” was funded. In this proposal we outline a broad research plan across the sprectrum of…

Proteomics of Filamentous Fungi

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Ellen Panisko
Our research is aligned with the DOE core mission to develop new sources of energy for the future. The biorefinery concept, which aims to make fuel from biomass economically feasible by the…

Proteomic studies of growth and metabolism in Corynebacterium glutamicum R

Lead Institution
Research Institute of Innovative Technology for the Earth
Principal Investigator
Hideaki Yukawa
Project type
Exploratory Research
Corynebacterium glutamicum is a soil bacterium isolated in Japan in the 1950's as an L-glutamic acid producer (Kinoshita, et al., 1957). Strains derived from C. glutamicum are used in a number…

The Schizophyllum commune proteome

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Scott Baker
Project type
Exploratory Research
Background The authors, have in parallel with this proposal, submitted a genome sequencing proposal to the DOE Microbial Genome Program (MGP) for Schizophyllum commune (see attached pdf). This…

Biology in Space and Time (BioSaT) Research Campaign

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Scott Baker
Significant research effort is currently aimed at developing cost effective plant biomass deconstruction for biofuel production. Moreover, the recalcitrance of plant cell walls to rapid degradation…

NMR Analysis of Bioprocess Samples

Lead Institution
Washington State University Tri-Cities
Principal Investigator
Kathleen McAteer
Project type
Limited Scope
NMR spectroscopy will be used to identify chemical components (metabolites) present in bioprocess samples from fungal fertmentations. The data will be collected in high-throughput mode as part of a…

NMR of Bioprocess Samples

Lead Institution
Washington State University Tri-Cities
Principal Investigator
Kathleen McAteer
Project type
Limited Scope
The overall project is directed towards utilization of filamentous fungi for conversion of complex biomass to industrial commodity chemicals -biofuels, organic acids or chemical feed-stocks for other…

Agile BioFoundry

Lead Institution
Pacific Northwest National Laboratory
Principal Investigator
Jon Magnuson
This proposed EMSL Resource Owner project, is a sub-project supporting two DOE-EERE-BETO supported PNNL projects: FY16-17 four-national laboratory “Agile BioFoundry” (ABF) seed project and a larger…

NMR Analysis of Bioprocess Samples

Lead Institution
Washington State University Tri-Cities
Principal Investigator
Kathleen McAteer
Project type
Large-Scale EMSL Research
The overall project is directed towards utilization of filamentous fungi for conversion of complex biomass to industrial commodity chemicals biofuels, organic acids or chemical feed-stocks for other…

Biology in Space and Time (BioSaT) Research Campaign

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Scott Baker
Significant research effort is currently aimed at developing cost effective plant biomass deconstruction for biofuel production. Moreover, the recalcitrance of plant cell walls to rapid degradation…

Agile BioFoundry

Lead Institution
Environmental Molecular Sciences Laboratory
Principal Investigator
Kristin Burnum-Johnson
This proposed EMSL Resource Owner project, is a sub-project supporting two DOE-EERE-BETO supported PNNL projects: FY16-17 four-national laboratory “Agile BioFoundry” (ABF) seed project and a larger…